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An aneurysm Aneurysm, abdominal: An aneurysm situated within the abdomen (belly). An aneurysm is a localized widening (dilatation) of an artery, vein, or the heart. At the area of an aneurysm, there is typically a bulge and the wall is weakened and may rupture. The word "aneurysm" comes from the Greek "aneurysma" meaning "a widening." See: Aneurysm, aortic.