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The nucleobase adenine is a type of nucleotide. It is one of the four nucleobases represented by the letters G–C–A–T in the nucleic acid of DNA. Guanine, cytosine, and thymine are the other three. Its derivatives, including the energy-rich adenosine triphosphate and the cofactors nicotinamide adenine dinucleotide, flavin adenine dinucleotide, and Coenzyme A, play a number of roles in biochemistry, including cellular respiration. It also serves as a chemical part of DNA and RNA and plays a role in protein synthesis. Adenine has a complementary form to thymine in DNA and uracil in RNA.
What is Adenine Made Of?
Adenine is the parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6. It has a role as a human metabolite, a Daphnia magna metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purine nucleobase and a member of 6-aminopurines.
Why must adenine always pair with thymine?
Adenine and thymine match up so that a hydrogen bond can form between the exocyclic amino group at C6 on adenine and the carbonyl at C4 in thymine; and likewise, a hydrogen bond can form between Nl of adenine and N3 of thymine.